BRAF V600E, TERT, and IDH2 Mutations in Pleomorphic Xanthoastrocytoma: Observations from a Large Case-Series Study

Chengxin Ma,Rui Feng,Hong Chen,N.U.Farrukh Hameed,Abudumijit Aibaidula,Yanyan Song,Jinsong Wu

WORLD NEUROSURGERY（2018）

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摘要

•The patients with BRAF V600E mutations were generally younger than those without it.•TERT promoter mutation frequency in patients with PXA was lower than in those with anaplastic PXA.•Patients with PXA with gross total resection have a better survival prognosis.

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关键词

Anaplastic,BRAF V600E,IDH2 R172K,Pleomorphic xanthoastrocytoma,Prognosis,TERT

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