T2 mapping MRI technique quantifies carotid plaque lipid, and its depletion after statin initiation, following acute myocardial infarction.
Atherosclerosis(2018)
摘要
•T2 mapping is a newly-validated magnetic resonance (MRI) technique that can quantify carotid lipid content in patients who were not pre-screened for carotid atherosclerosis.•T2 mapping can detect reduction in carotid lipid content following three months of statin treatment.•This reduction in plaque lipid was not related to blood lipid measurements suggesting that these measurements are not substitutes for quantifying plaque lipid.•These findings support the use of plaque imaging to identify patients who may be suitable for intensive lipid treatments.
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关键词
Carotid plaque,Atherosclerosis,Lipid,Statin,T2 mapping,Biomarkers
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