Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.

•UVB-induced collagen-I reduction, oxidative stress and cytotoxicity could be partially rescued by astragaloside.•UVB-induced ERK and p38 activation could be repressed by astragaloside.•UVB-suppressed autophagy could be reversed by astragaloside.•Astragaloside upregulates UVB-reduced collagen-I by enhancing autophagy.