FABP7 promotes cell proliferation and survival in colon cancer through MEK/ERK signaling pathway.

Biomedicine & Pharmacotherapy(2018)

引用 21|浏览5
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摘要
•FABP7 is significantly up-regulated in colon cancer tissues and cell lines.•FABP7 promotes colon cancer cell proliferation and inhibits apoptosis.•FABP7 knockdown inhibits tumor growth in vivo.•MEK/ERK pathway mediates the effects of FABP7 on colon cancer cells.
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关键词
FABP7,Cell survival,MEK/ERK pathway,Colon cancer
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