Inflammatory markers of CHMP2B-mediated frontotemporal dementia

Peter Roos,Marina Rode von Essen,Troels Tolstrup Nielsen,Peter Johannsen,Jette Stokholm, Anne Sigaard Bie,Gunhild Waldemar,Anja Hviid Simonsen,Amanda Heslegrave,Henrik Zetterberg,Finn Sellebjerg,Jørgen Erik Nielsen

Journal of Neuroimmunology（2018）

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摘要

Histopathological studies and animal models have suggested an inflammatory component in the pathomechanism of the CHMP2B associated frontotemporal dementia (FTD-3).

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关键词

Autosomal dominantly inherited frontotemporal dementia,Chromosome 3-linked frontotemporal dementia (FTD-3),CHMP2B,Inflammation,TREM2

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