Effect of Losartan on Mitral Valve Changes After Myocardial Infarction.

Philipp E Bartko,Jacob P Dal-Bianco,J Luis Guerrero,Jonathan Beaudoin,Catherine Szymanski,Dae-Hee Kim, Margo M Seybolt,Mark D Handschumacher,Suzanne Sullivan,Michael L Garcia,James S Titus,Jill Wylie-Sears,Whitney S Irvin,Emmanuel Messas,Albert A Hagège,Alain Carpentier,Elena Aikawa,Joyce Bischoff,Robert A Levine

Journal of the American College of Cardiology（2017）

引用 99|浏览0

暂无评分

摘要

Profibrotic changes of tethered MV leaflets post-MI can be modulated by losartan without eliminating adaptive growth. Understanding the cellular and molecular mechanisms could provide new opportunities to reduce ischemic MR.

查看译文

关键词

CD45,endothelial-to-mesenchymal transition,ischemic mitral regurgitation,losartan,TGF-β,VCAM-1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要