Humoral and cellular immunity to RSV in infants, children and adults.

C A Green,C J Sande,C de Lara,A J Thompson, L Silva-Reyes, F Napolitano,A Pierantoni,S Capone,A Vitelli,P Klenerman,A J Pollard

Vaccine（2018）

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摘要

Repeated RSV exposure in early life generates immune responses that are inversely related to frequency of severe disease. Induction of F-specific antibody and cellular immune responses through infant vaccination might help to accelerate the development of protective immune responses at an early age. Clinicaltrials.gov reference NCT01563692 and NCT01640652.

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关键词

Respiratory syncytial virus,Immune responses,Healthcare workers,Infants

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