Sargassum polysaccharide inhibits inflammatory response in PCV2 infected-RAW264.7 cells by regulating histone acetylation.

Hai-Lan Chen,Hong-Lian Tan,Jian Yang,Ying-Yi Wei,Ting-Jun Hu

Carbohydrate Polymers（2018）

引用 14|浏览15

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摘要

•Sargassum polysaccharide (SP) attenuates virus induced inflammatory response.•SP modulates the activities of histone acetyltransferases and deacetylases.•SP inhibits histone acetylation in infected cells.

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关键词

SP,PCV2,HATs,HDACs,H3,TNF-α,IL-,MCP,COX-,PMWS,HIV-1,DMEM,FBS,DMSO,LPS,TSA,MTT,RT-PCR,OD,ELISA,TLR,PPV,Ac-CoA

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