Motor function in an animal model with ouabain-induced bipolar disorder and comorbid anxiety behavior.

Psychiatry Research(2018)

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摘要
•The high concentration of ouabain induced comorbid anxiety and hyperactivity.•The study is the first animal model of comorbid anxiety and bipolar disorder.•Our study offers insights for comorbid anxiety and bipolar disorder in clinics.
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关键词
Ouabain,Bipolar disorder,Open field test,Locomotor activity,Anxiety behavior
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