A portrait of germline mutation in Brazilian at-risk for hereditary breast cancer.

Ana Rafaela de Souza Timoteo, Ana Élida Menezes Magalhães Gonçalves, Lucas Amadeus Porpino Sales,Betina Menezes Albuquerque,Jorge Estefano Santana de Souza,Patrícia Cristina Pascoto de Moura, Marcos Alberto Arruda de Aquino,Lucymara Fassarela Agnez-Lima,Tirzah Braz Petta Lajus

Breast cancer research and treatment（2018）

引用 18|浏览13

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摘要

This work highlights the benefits of large-scale sequencing for oncogenetic counseling and extends our understanding about the genetics of hereditary breast cancer in the multi-ethnic Brazilian population.

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关键词

ATR germline mutation,Hereditary breast cancer,Moderate-risk genes,Multigene testing,Oncogenetic counseling

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