Staphylococcus aureus lipoproteins augment inflammatory responses in poly I:C-primed macrophages.

Cytokine(2018)

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摘要
•S. aureus lipoproteins induce inflammatory responses in macrophages.•S. aureus lipoproteins augment IL-6 production in poly I:C-primed macrophages.•IFN-β is involved in the excessive IL-6 production in poly I:C-primed macrophages.•PI3K, Akt, ERK and NF-κB are associated with the enhancement of IL-6 production.
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关键词
Staphylococcus aureus,Lipoproteins,Viral infection,Secondary infection,Inflammation
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