Amentoflavone induces apoptosis and suppresses glycolysis in glioma cells by targeting miR-124-3p.

Wang Zhaohui, Niu Yingli, Lin Hongli,Wang Haijing,Zhang Xiaohua, Fang Chao, Wu Liugeng,Zhang Hui, Tian Feng, Yang Linfeng,Jiang Hong

Neuroscience Letters（2018）

引用 33|浏览6

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摘要

•AF suppressed glioma cells.•AF induced apoptosis and inhibited glycolysis.•AF upregulated miR-124-3p by repressing DNMT1 through Sp1, which caused by activation of ROS/AMPK.

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关键词

Amentoflavone,Glioma,Apoptosis,Glycolysis,miR-124-3p,DNMT1

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