RAP2 mediates mechanoresponses of the Hippo pathway

Kimberly C Lin
Kimberly C Lin
Cao Fang
Cao Fang
Shicong Lu
Shicong Lu
Margaret Pan
Margaret Pan
Min Luo
Min Luo

Nature, 2018.

Cited by: 16|Bibtex|Views55|Links
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Abstract:

Mammalian cells are surrounded by neighbouring cells and extracellular matrix (ECM), which provide cells with structural support and mechanical cues that influence diverse biological processes. The Hippo pathway effectors YAP (also known as YAP1) and TAZ (also known as WWTR1) are regulated by mechanical cues and mediate cellular responses...More

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