Assessment of one-dose mumps-containing vaccine effectiveness on wild-type genotype F mumps viruses circulating in mainland China.

Aili Cui,Zhen Zhu,Naiying Mao,Yuan Si,Yu Ma,Ying Hu,Xiuying Deng,Liping Wang,Lingjia Zeng,Yan Zhang,Wenbo Xu

Vaccine（2018）

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摘要

•One-dose MuCV had a limited effectiveness on wild-type genotype F MuV strains.•Second-dose MuCV is highly recommended to increase MuV neutralizing antibody titers.•A poor linear correlation between mumps IgG concentration and neutralization titer.

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关键词

Mumps virus,Mumps-containing vaccine effectiveness,Antigenic variation,Cross-neutralization

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