Effectiveness of increasing the frequency of posaconazole syrup administration to achieve optimal plasma concentrations in patients with haematological malignancy
International Journal of Antimicrobial Agents(2016)
摘要
•Increasing the frequency of posaconazole syrup is effective for adjusting drug levels.•Optimal drug levels are not achieved when steady-state level is <200 ng/mL.•In only 5.3% (6/114), drug levels remained suboptimal despite dose adjustment.
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关键词
Posaconazole,Syrup,Leukaemia,Therapeutic drug monitoring,Concentration
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