Treatment outcomes and incidence of brain metastases in pulmonary large cell neuroendocrine carcinoma.

Yizhou Zhao,Mathieu Castonguay,Derek Wilke,Zhaolin Xu,Madelaine Plourde,Liam Mulroy,Mary MacNeil,David Bowes

Current Problems in Cancer（2019）

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摘要

LCNEC's survival outcomes are poor. The incidence of brain metastases is higher than what is observed for other types of nonsmall cell lung cancers. Prophylactic cranial irradiation should be investigated as a means of improving outcomes.

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关键词

Large cell neuroendocrine carcinoma,Brain metastasis,Pattern of recurrence,Prophylactic cranial irradiation

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