Bupropion attenuates morphine tolerance and dependence: Possible role of glutamate, norepinephrine, inflammation, and oxidative stress.

Mostafa Mahmoud Hamdy,Mohamed Mostafa Elbadr,Ahmed Barakat

Pharmacological Reports（2018）

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摘要

Bupropion efficacy in attenuation of morphine tolerance and dependence with its high safety and tolerability profile provide an alternative option to conventional agents e.g., ketamine and clonidine to modulate these phenomena.

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关键词

Bupropion,Analgesia,Morphine tolerance,Dependence

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