Children are particularly vulnerable to environmental tobacco smoke exposure: Evidence from biomarkers of tobacco-specific nitrosamines, and oxidative stress.

Environment International(2018)

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摘要
•Children had a significantly lower ability to detoxify NNK than adults.•Urinary total NNAL:cotinine ratio could inform on the ETS exposure source.•In children, THS might be a more important source of NNK exposure than SHS.•Children have a higher risk of ETS health effects, e.g., oxidative stress.
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8-oxodGuo,Cr,ESI,ETS,LC-MS/MS,LOD,NNAL,NNAL-Gluc,NNK,SHS,SPE,THS,TSNA
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