Tertiary lymphoid organs: A novel target in patients with chronic rhinosinusitis.

Sathish Paramasivan,Susan Lester,Aden Lau,Judy Ou,Alkis James Psaltis,Peter-John Wormald,Sarah Vreugde

The Journal of allergy and clinical immunology（2018）

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摘要

TLOs are associated with a distinct, proinflammatory gene-expression profile in CRS. Recognising these patients as a distinct endotype may assist in prognosis and individualised management.

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