Verification of HE-based CTV in laryngeal and hypopharyngeal cancer using pan-cytokeratin.

Hans Ligtenberg,Stefan M Willems,Lilian N Ruiter,Elise Anne Jager,Chris H J Terhaard,Cornelis P J Raaijmakers,Marielle E P Philippens

Clinical and Translational Radiation Oncology（2018）

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摘要

•Currently clinical CTV margins lack evidence and need (histopathological) validation.•Tumor outline on HE and pan-cytokeratin staining are comparable for laryngeal cancer.•HE-based delineations can be used for histopathology based CTV-margin definition.

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关键词

HE,CTV,CT,MRI,FDG-PET,CI,p95,GTV,SCC,CK-AE1/3,TLE,HIER,PBS,DAB,TME

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