Human mesenchymal stromal cells do not promote recurrence of soft tissue sarcomas in mouse xenografts after radiation and surgery

Paola A Filomeno
Paola A Filomeno
Kyung-Phil Kim
Kyung-Phil Kim
Nara Yoon
Nara Yoon
Andrea Filomeno
Andrea Filomeno

Cytotherapy, 2018.

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Keywords:
human mesenchymal stromal cellsregenerative medicinesoft tissue sarcomatumor xenograft modelwound healing

Abstract:

These studies are important for the establishment of a safety profile for MSC administration in patients with STS. Our data suggest that MSCs are safe in STS management after standard of care RT/surgery, which can be further investigated in early-phase clinical trials to also determine the efficacy of MSCs in reducing morbidity and to mit...More

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