Leukocytosis, prognosis biomarker in locally advanced head and neck cancer patients after chemoradiotherapy.

Antoine Schernberg,Pierre Blanchard,Cyrus Chargari,Dan Ou,Antonin Levy,Philippe Gorphe,Ingrid Breuskin,Sarah Atallah,Alexandre Caula,Alexandre Escande,François Janot,France Nguyen,Stéphane Temam,Eric Deutsch,Yungan Tao

Clinical and Translational Radiation Oncology（2018）

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摘要

•In locally advanced HNSCC, baseline leukocytosis predicts OS and PFS.•Respectively 24% and 20% patients displayed baseline leukocytosis or neutrophilia.•This independent biomarker could help identifying patients with high risk of tumor relapse.

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关键词

Head and neck cancer,Squamous cell carcinoma,Concurrent chemoradiation,Prognostic factor,Biomarkers,Neutrophilia,Leukocytosis

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