Reprogramming glioblastoma multiforme cells into neurons by protein kinase inhibitors.

Jie Yuan,Fan Zhang,Dennis Hallahan,Zhen Zhang,Liming He,Ling-Gang Wu,Meng You,Qin Yang

Journal of experimental & clinical cancer research : CR（2018）

引用 12|浏览13

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摘要

This study indicates that ROCK and mTOR inhibitors-based reprogramming treatment prevents GBM local recurrence. Currently ROCK-mTOR inhibitors are used as anti-tumor drugs in patients, so this reprogramming strategy has significant potential to move rapidly toward clinical trials.

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关键词

GBM,mTOR,Neuron,Protein kinase inhibitors,Reprogramming,ROCK

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