Evaluation of a mosaic HIV-1 vaccine in a multicentre, randomised, double-blind, placebo-controlled, phase 1/2a clinical trial (APPROACH) and in rhesus monkeys (NHP 13-19).

Dan H Barouch,Frank L Tomaka,Frank Wegmann,Daniel J Stieh,Galit Alter,Merlin L Robb,Nelson L Michael,Lauren Peter,Joseph P Nkolola,Erica N Borducchi,Abishek Chandrashekar,David Jetton,Kathryn E Stephenson,Wenjun Li,Bette Korber,Georgia D Tomaras,David C Montefiori,Glenda Gray,Nicole Frahm,M Juliana McElrath,Lindsey Baden,Jennifer Johnson,Julia Hutter,Edith Swann,Etienne Karita,Hannah Kibuuka,Juliet Mpendo,Nigel Garrett,Kathy Mngadi,Kundai Chinyenze,Frances Priddy,Erica Lazarus,Fatima Laher,Sorachai Nitayapan,Punnee Pitisuttithum,Stephan Bart,Thomas Campbell,Robert Feldman,Gregg Lucksinger, Caroline Borremans,Katleen Callewaert, Raphaele Roten,Jerald Sadoff, Lorenz Scheppler,Mo Weijtens,Karin Feddes-de Boer,Daniëlle van Manen,Jessica Vreugdenhil,Roland Zahn,Ludo Lavreys,Steven Nijs,Jeroen Tolboom,Jenny Hendriks,Zelda Euler,Maria G Pau,Hanneke Schuitemaker

The Lancet（2018）

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摘要

Janssen Vaccines & Prevention BV, National Institutes of Health, Ragon Institute of MGH, MIT and Harvard, Henry M Jackson Foundation for the Advancement of Military Medicine, US Department of Defense, and International AIDS Vaccine Initiative.

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