Comparison of up-front radiotherapy and TKI with TKI alone for NSCLC with brain metastases and EGFR mutation: A meta-analysis

Chunyu Wang,Xiaotong Lu,Zhangyan Lyu,Nan Bi,Luhua Wang

Lung Cancer（2018）

引用 42|浏览6

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摘要

•Up-front radiotherapy and TKI showed better intracranial PFS and OS than TKI alone.•The published papers evaluating the role of RT had high heterogeneity.•Patients with less number of brain metastases benefited more from RT treatment.

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Non-small cell lung cancer,EGFR mutation,Brain metastases,Radiotherapy,Tyrosine kinase inhibitor

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