Colloidal Polymeric Platform for Facile Click-Assisted Ligand Functionalization and Receptor Targeting.
ACS omega(2016)
摘要
Colloidal poly(glycidyl methacrylate) nanoparticles (NPs) are demonstrated to be platforms facilitating the "click" chemistry approach of surface functionalization for receptor targeting. Folate receptor-targeted NPs were synthesized, physicochemically characterized, confirmed for their biocompatibility, and validated for their selective targeting capabilities for ovarian cancer cells in vitro.
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