Carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis overlap in a Filipino with positive HLA-B75 serotype.

Francis Capule,Pramote Tragulpiankit,Surakameth Mahasirimongkol,Nuanjun Wichukchinda,Jiraphun Jittikoon,Lara Theresa Alentajan-Aleta,Jay-V James Barit,Josephine Casanova-Gutierrez,Leonor Cabral-Lim,Jose Paciano Baltazar Reyes,Francisca Roa,Katrina Faith San Gabriel,Catherine Lynn Silao

BMJ case reports（2018）

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摘要

Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two related mucocutaneous disorders with different severities. Although the incidence is low, SJS and TEN are life-threatening and predominantly drug-induced conditions. There is a strong relationship between the HLA-B*1502HLA-B*1502

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genetics,pharmacology and therapeutics

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