Toxicological safety evaluation of freeze-dried Protaetia brevitarsis larva powder.

Jung-Ho Noh,Ji-Seong Jeong,Sang-Jin Park,Eun-Young Yun,Jae Sam Hwang,Ji-Young Kim,Kyung-Jin Jung,Hee Jin Park,Hwa-Young Son,Kyoung-Sik Moon

Toxicology Reports（2018）

引用 16|浏览13

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摘要

•General toxicity and genotoxicity of freeze-dried P. brevitarsis larva powder was investigated.•In rats, LD50 and NOAEL set at >5000 and 3000 mg/kg, respectively.•No aberrant changes in Ig E and histamine concentration were observed in the 13-week oral repeated dose study.•No evidence of mutagenic and carcinogenic potential was observed in the genotoxicity studies.

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关键词

Protaetia brevitarsis larva,Edible insect,Single-dose oral toxicity,13-week oral toxicity,Genotoxicity

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