MicroRNA-298 represses hepatocellular carcinoma progression by inhibiting CTNND1-mediated Wnt/β-catenin signaling.

Ningjia Cao,Liang Mu,Wei Yang,Li Liu,Liang Liang, Hong Zhang

Biomedicine & Pharmacotherapy（2018）

引用 25|浏览4

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摘要

•miR-298 is obviously down-regulated in HCC tissues and cells.•miR-298 inhibits HCC cell proliferation and metastasis.•CTNND1 is a direct target of miR-298 in HCC.•CTNND1 at least partially mediates the tumor suppressive role of miR-298 in HCC.

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关键词

HCC,HBV,miRNAs,EMT,EZH2,CTNND1,RT-qPCR,HRP,CCK-8,PI

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