Chemical synthesis of 7α-hydroxypregnenolone, a neuroactive steroid that stimulates locomotor activity.
Steroids(2017)
摘要
•Two convenient approaches for the synthesis of 7α-hydroxypregnenolone are reported.•Explanation of the stereoselectivity of reduction at C7-ketone.•Potential application to other steroid analogs oxygenated at C7.
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关键词
GABA,NMR,CYP,TLC
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