Clinical Decision Support to Efficiently Identify Patients Eligible for Advanced Heart Failure Therapies.

•Many heart failure (HF) patients who could benefit from advanced therapies are not referred as soon as they should be.•We developed a computer application with sufficient data access and a high enough level of clinical decision support logic that promotes timely and appropriate referral for advanced HF therapies.•Intervention patients were referred to specialized heart facilities significantly more often within 30 days (57% vs 34%; P < .001), 60 days (69% vs 44%; P < .0001), 90 days (73% vs 49%; P < .0001), and 180 days (79% vs 58%; P < .0001) than control patients.•Significantly more intervention patients were found to be alive at 30 days (95% vs 92%; P = .036) at 60 days (95% vs 90%; P = .0013), 90 days (94% vs 87%; P = .0002), and 180 days (92% vs 84%; P = .0001) than control patients.