miR-133a function in the pathogenesis of dedifferentiated liposarcoma.

Peter Y Yu,Gonzalo Lopez,Danielle Braggio,David Koller,Kate Lynn J Bill,Bethany C Prudner,Abbie Zewdu,James L Chen,O Hans Iwenofu,Dina Lev,Anne M Strohecker,Joelle M Fenger,Raphael E Pollock,Denis C Guttridge

Cancer cell international（2018）

引用 13|浏览42

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摘要

Based on our collective findings, we propose that in DDPLS, loss of miR-133a induces a metabolic shift due to a reduction in oxidative metabolism favoring a Warburg effect in DDLPS tumors, but this regulation on metabolism was not sufficient to affect DDPLS.

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关键词

Sarcoma,Dedifferentiated liposarcoma,miR-133a,Metabolism

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