Neuropilin 1 (NRP1) is a novel tumor marker in hepatocellular carcinoma.

Jiafei Lin,Yingwei Zhang,Jiemin Wu,Li Li,Ning Chen,Peihua Ni,Lihua Song,Xiangfan Liu

Clinica Chimica Acta（2018）

引用 33|浏览19

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摘要

•The −1848 ~ −1841 region in the NRP1 promoter is critical for TEAD binding.•NRP1 is specifically up-regulated in the serum of HCC patients.•Serum NRP1 is significantly associated with AFP and other liver function markers.•The AUC-ROC for serum NRP1 0.971 which is better than AFP.

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关键词

TEAD,AUC-ROC,AFP,Cutoff value,Diagnosis

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