Of mice and motion: Behavioural-EEG phenotyping of Alzheimer's disease mouse models.

Barry Crouch, Jie Min Yeap, Bianca Pais,Gernot Riedel,Bettina Platt

Journal of Neuroscience Methods（2019）

引用 7|浏览8

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摘要

•Event stamping enables alignment between behavioural observation and EEG sampling.•Controlling for speed is critical when quantifying EEG.•Hippocampal EEG Gamma response to speed is deficient in Alzheimer mice.•EEG response to direction remain intact in Alzheimer mice.•EEG response to correct vs incorrect y-maze alternations is affected in transgenic mice.

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关键词

EEG,Behaviour,Spectral analysis,Autoregressive modelling,Theta,Gamma,Speed,Motion,Y-maze,Amyloid precursor protein

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