Interleukin 15 blockade protects the brain from cerebral ischemia-reperfusion injury.

Gilbert Aaron Lee,Teng-Nan Lin,Cheng-Yu Chen, Shin-Yi Mau,Wan-Zhen Huang,Yu-Chieh Kao,Ruo-Yu Ma,Nan-Shih Liao

Brain, Behavior, and Immunity（2018）

引用 58|浏览11

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摘要

•IL-15 system aggravates the brain injury after cerebral ischemia-reperfusion.•Post-ischemia IL-15 blockade reduces brain injury and improves motor function.•Post-ischemia IL-15 blockade reduces NK, CD8+ and CD4+ T cell effector function.

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关键词

NK cell,PMN,IL-15,Th1,WT,HI

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