Interfering effects of bisphenol A on in vitro growth of preantral follicles and maturation of oocyes.

Clinica Chimica Acta(2018)

引用 25|浏览13
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摘要
•BPA interferes with mouse follicle growth and estrogen production.•BPA decreases GDF-9 and BMP-15 expression, and disrupts oocyte meiotic division.•BPA decreases the expressions of p-Erk1 and p-CaMK II and inhibits granulosa cells proliferation.
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关键词
Bisphenol A (BPA),Preantral follicles,GDF-9,BMP-15,P-Erk1,P-CaMKII
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