TRIMming TGF-β signals in Th17 cells.
JOURNAL OF EXPERIMENTAL MEDICINE(2018)
摘要
The precise downstream mediators of TGF-beta signaling in Th17 and T reg cells remain unclear. In this issue of JEM, Tanaka et al. report that Trim33 transduces TGF-beta signals in Th17 cells to generate an optimal proinflammatory cytokine profile.
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