Inflammation Associates With Impaired Small Arterial Elasticity Early in HIV Disease.

Tess E Peterson,Katherine Huppler Hullsiek,Nicole Wyman Engen,Nagalingeswaran Kumarasamy,Anne-Mette Lebech,Angelike Liappis,Antonios Papadopoulos,Mark N Polizzotto,Pamela J Schreiner,Daniel Duprez,Jason V Baker

OPEN FORUM INFECTIOUS DISEASES（2018）

引用 7|浏览25

暂无评分

摘要

We estimated small arterial elasticity and used linear regression to evaluate its association with inflammatory biomarkers among antiretroviral therapy-naive, HIV-positive patients with high CD4+ counts. After adjustment, high-sensitivity C-reactive protein and interleukin-6 were inversely associated with small arterial elasticity. These data suggest that systemic inflammation may contribute to vascular dysfunction even in very early HIV disease.

查看译文

关键词

arterial elasticity,cardiovascular disease,HIV infection,systemic inflammation,vascular dysfunction

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要