Knockdown of TRIM66 inhibits malignant behavior and epithelial-mesenchymal transition in non-small cell lung cancer.

Huan-Yu Dai,Yan Ma,Zhao Da,Xiao-Ming Hou

Pathology - Research and Practice（2018）

引用 20|浏览18

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摘要

Silence TRIM66 expression suppressed NSCLC cell proliferation, invasion, and migration. The siRNA-mediated TRIM66 silencing could block the occurrence of EMT. TRIM66 could be a promising novel target for future NSCLC treatments.

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关键词

NSCLC,TRIM66,EMT,Malignant phenotype

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