RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.

•RNA-Seq analysis was performed on Atlantic cod precision cut liver slices exposed to BaP, EE2, and mixtures of BaP and EE2 for 48 h.•Genes and pathways related to Ahr and estrogen receptor pathways were affected by BaP and EE2 treatments, respectively.•EE2 treatment resulted in up-regulation of fgf3 and fgf4 genes, suggesting effects on FGF signaling in fish.•BaP appeared to have anti-estrogenic effects in the mixture treated groups.