Interleukin-5 suppresses Vascular Endothelial Growth Factor-induced angiogenesis through STAT5 signaling.

Felicitas Bucher,Jungho Lee,Sanghee Shin,Minseok S Kim,Yong-Seok Oh,Sanghoon Ha,Hongkai Zhang,Kyungmoo Yea

Cytokine（2018）

引用 14|浏览6

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摘要

•IL-5 down-regulates the VEGF-induced angiogenesis of lung microvascular endothelial cells via STAT5 signaling.•This study implies that IL-5 may contribute to the regulation of vascularization in lung tissue as well as the eosinophil-associated lung disease.

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关键词

Interleukin-5,VEGF,Angiogenesis,Endothelial,STAT5

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