Insulin decreases expression of the proinflammatory receptor proteinase-activated receptor-2 on human airway epithelial cells.
The Journal of allergy and clinical immunology(2018)
摘要
The authors show that insulin, a hormone with anti-inflammatory properties, decreases the expression of a pro-inflammatory receptor on airway epithelial cells. This observation may explain the heightened respiratory inflammation seen in patients with metabolic syndrome.
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