Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.

Daniel Lightwood, Markus Tservistas, Monique Zehentleitner,Kaushik Sarkar,Alison Turner,Marguerite Bracher,Bryan Smith,Sabrina Lamour,Tim Bourne,Stevan Shaw,Neil Gozzard,Roger T Palframan

American journal of respiratory and critical care medicine（2018）

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摘要

Inhaled CDP7766 potently inhibited the function of IL-13 generated during the airway response to inhaled allergen in cynomolgus macaques, demonstrating the potential of inhaled anti-IL-13 therapeutics for the treatment of allergic asthma.

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Ascaris suum,allergen,therapeutics

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