Cissus quadrangularis extract (CQR-300) inhibits lipid accumulation by downregulating adipogenesis and lipogenesis in 3T3-L1 cells.

Hae Jin Lee,Bao Le,Dong-Ryung Lee,Bong-Keun Choi,Seung Hwan Yang

Toxicology Reports（2018）

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摘要

•CQR-300 inhibited lipid accumulation in 3T3-L1 adipocytes.•CQR-300 inhibited the differentiation of adipocytes by regulating adipogenesis.•CQR-300 reduced fatty acids and triglyceride accumulation via downregulating lipogenesis.

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关键词

ACC,AMPK,aP2,BCS,C/EBPα,CQR-300,DMEM,FAS,FAS-α,FBS,GAPDH,LPL,MDI,MTT,ORO,p-AMPK,PPARγ,RIPD,SCD-1,SREBP-1c,TG

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