Neuropeptide Y is up-regulated and induces antinociception in cancer-induced bone pain.

Marta Diaz-delCastillo,Søren H Christiansen,Camilla K Appel,Sarah Falk,David P D Woldbye,Anne-Marie Heegaard

Neuroscience（2018）

引用 13|浏览20

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摘要

•Neuropeptide Y is up-regulated in the spinal cord of cancer-bearing rats.•Intrathecal neuropeptide Y induces antinociception in cancer-induced bone pain.•The antinociceptive effect of neuropeptide Y is mediated by both Y1 and Y2 receptors.

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关键词

BSA,CTCF,EDTA,,FBS,GABA,GDNF,HBSS,HEPES,,NPY,PDGF,PYY,RT,Y1R,Y2R

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