MicroRNA-133a Impairs Perfusion Recovery after Hindlimb Ischemia in Diabetic Mice
Bioscience reports, 2018.
reactive oxygen speciesMicroRNA-133aangiogenesisnitric oxideperipheral arterial disease
Peripheral arterial disease (PAD) patients with diabetes mellitus suffer from impaired neovascularization after ischemia which results in poorer outcomes. MicroRNA (miR)-133a is excessively expressed in endothelial cells under diabetic conditions. Here, we test whether diabetes-induced miR-133a upregulation is involved in the impaired ca...More
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