Early growth response gene 1 is essential for urban particulate matter-induced inflammation and mucus hyperproduction in airway epithelium.

Feng Xu,Jiaofei Cao,Man Luo,Luanqing Che,Wen Li,Songmin Ying,Zhihua Chen,Huahao Shen

Toxicology Letters（2018）

引用 22|浏览20

暂无评分

摘要

•PM induced Egr-1 expression in vitro and in vivo.•Egr-1 positively regulated PM-induced inflammation and mucus hyperproduction.•Egr-1 modulated inflammation response via the NF-κB pathway.•Egr-1 modulated mucus production via the AP-1 pathway.

查看译文

关键词

Particulate matter,Early growth response gene 1,Airway inflammation,Mucus hyperproduction,Nuclear factor κB,Activator protein 1

AI 理解论文

溯源树

样例

生成溯源树，研究论文发展脉络

Chat Paper

正在生成论文摘要