Pirfenidone Ameliorates Lipopolysaccharide-Induced Pulmonaryinflammation And Fibrosis By Blocking Nlrp3 Inflammasome Activation
Molecular Immunology（2018）
摘要
•Fibroproliferation is present early in LPS-induced acute lung injury.•Pirfenidone ameliorates LPS-induced pulmonary inflammation and fibrosis.•The efficacy of pirfenidone is associated with inhibition of NLRP3 inflammasome activation.
更多查看译文
关键词
LPS,ALI,ARDS,NLRP3,ASC,PFD,NAC,ROS
AI 理解论文
溯源树
样例
生成溯源树，研究论文发展脉络
Chat Paper
正在生成论文摘要