Comprehensive targeted super-deep next generation sequencing enhances differential diagnosis of solitary pulmonary nodules
Journal of thoracic disease, Volume 10, Issue Suppl 7, 2018.
Solid pulmonary nodulecirculating tumour DNA (ctDNA)early diagnosislung cancertumor mutational burden (TMB)
These results showed that lung cancer gene-targeted deep capture sequencing is not efficient enough to achieve ideal sensitivity by simply increasing the sequencing depth of ctDNA from early candidates. The sequencing could not be evaluated hotspot mutations in the early tumour stage. Nevertheless, a larger cohort is required to optimize ...More
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