Comprehensive targeted super-deep next generation sequencing enhances differential diagnosis of solitary pulmonary nodules

    Shiyong Li
    Shiyong Li
    Weizhe Huang
    Weizhe Huang
    Chunli Wang
    Chunli Wang
    Liping Liu
    Liping Liu
    Jilong Liu
    Jilong Liu
    Qiuhua Deng
    Qiuhua Deng
    Weizhe Huang
    Weizhe Huang

    Journal of thoracic disease, Volume 10, Issue Suppl 7, 2018.

    Cited by: 1|Bibtex|Views8|Links
    WOS
    Keywords:
    Solid pulmonary nodulecirculating tumour DNA (ctDNA)early diagnosislung cancertumor mutational burden (TMB)

    Abstract:

    These results showed that lung cancer gene-targeted deep capture sequencing is not efficient enough to achieve ideal sensitivity by simply increasing the sequencing depth of ctDNA from early candidates. The sequencing could not be evaluated hotspot mutations in the early tumour stage. Nevertheless, a larger cohort is required to optimize ...More

    Code:

    Data:

    Your rating :
    0

     

    Tags
    Comments