Early Env-specific CTLs effectively suppress viral replication in SHIV controller macaques

Jin Fan,Hua Liang,Tao Shen,Shuo Wang,Xiaolin Ji,Cassian Yee,Fengmin Lu,Yiming Shao

Cellular Immunology（2018）

引用 5|浏览11

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摘要

•Early Env-specific CD8 T cell responses contributed substantially to the control of viral replication.•Env-specific CTL maintained phenotype and function in culture.•Early Env-specific CTL can suppress viral replication in SHIV-infected CD4.•Early Env-specific CTL can-not suppress viral replication in SHIV-infected macrophages.

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关键词

SHIV,Acute infection,Function,CTL,Env

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